Macrophagic myofasciitis

Macrophagic Myofasciitis, or MMF, is a rare muscle disease identified in 1993. The disease is characterized by microscopic lesions found in muscle biopsies that show infiltration of muscle tissue by PAS-positive macrophages.[1] Specific causes of MMF are unknown, but the disease is most often associated with the pathological persistence of aluminium hydroxide used in some vaccines. Clinical symptoms include muscle pain, joint pain, muscle weakness, fatigue, fever, and muscle tenderness. A diagnosis can only be identified with an open muscle biopsy of the vaccinated muscle.[2]

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References

  1. ^ Cherin P, Authier F-J, Creange1 A, Creange A et al. (May 2001). "Central nervous system disease in patients with macrophagic myofasciitis". Brain 124 (5): 974–983. doi:10.1093/brain/124.5.974. ISSN 1460-2156. OCLC 39378352. PMID 11335699. http://brain.oxfordjournals.org/cgi/content/full/124/5/974. Retrieved 2009-05-14. 
  2. ^ Fischer D, Reimann J, Schröder R (31 October 2003). "Macrophagic myofasciitis: inflammatory, vaccination-associated muscular disease". Dtsch Med Wochenschr 128 (44): 2305–2308. doi:10.1055/s-2003-43184. ISSN 1439-4413. OCLC 163397752. PMID 14593574. http://www.thieme-connect.de/ejournals/html/dmw/doi/10.1055/s-2003-43184. Retrieved 2009-05-14.